Management

 

AISscoliscoli

 

Curve Progression 

 

Typically thought that curves > 45 - 50o continue to progress after skeletal maturity 

 

Lonstein and Carlson JBJS Am 1985

- 727 patients with scoliosis followed to skeletal maturity

- 23% progressed

- correlation to magnitude curve / chronological age / Risser sign / menarche

 

Weinstein and Ponseti et al JBJS Am 1983

- 102 patients followed for 40 years

- 68% of curves progressed after skeletal maturity

- curves <  30o did not progress

- thoracic curves > 50 - 75o progressed most ( 1o/ year ) 

 

Options

 

Cobb Angle High growth potential / Risser 0 - 2 Low growth potential
<20°  Observe Observe / discharge
20°-30°   Observe / brace Observe
30°-45°   Brace Observe
>45°    Surgery Surgery / observe

 

Exercises

 

Dimitrijevic et al Eur Spine J 2022

- systematic review of Schroth method and core stabilization exercises

- positive effect on Cobb angle / trunk rotation / QOL

 

Bracing 

 

Indications

 

Typically prevent curve progression / will not correct or reverse curve

 

1.  Risser 0-2 (growth potential)

2.  Curve >30o adolescent

3.  Curve >25o with progression (5o in six months)

4.  Willingness to comply - must wear 18 - 23 hours a day until skeletal maturity

 

Types

 

Milwaukee Brace / CTLSO Boston brace / TLSO 

For curves with apex above T8

- pelvic piece over iliac crests connected to neck piece

- thoracic and lumbar pads

For curves with apex under T8
Milwaukee brace Boston brace

 

Results

 

Bracing

 

Negrini et al Spine 2016

- systematic review of full time braces in adolescent idiopathic scoliosis

- good evidence that braces prevent curve progression

 

Night time bracing

 

Kodra et al J Pediatr Soc North Am 2026

- systematic review of Providence night time bracing

- good evidence of prevention of curve progression

- likely similar efficacy to full time bracrs

 

Operative Management

 

Indications 

 

Typically thought that curves > 45 - 50o continue to progress after skeletal maturity  and require surgical intervention

 

Indications for surgery

- Cobb > 45 - 50o

- progression of curve

- significant cosmetic deformity

- significant coronal or sagittal imbalance

 

ScoliScoli

 

Principles

 

Obtain solid arthrodesis with correction of deformity and coronal / sagittal plane balance

 

Fuse minimal segments while obtaining adequate correction

- involving lumbar segments associated with early degeneration of unfused segments

- risk back pain

 

Options

 

Posterior instrumented fusion 

Anterior instrumented fusion 

Anterior vertebral body tethering

 

Posterior Instrumented fusion

 

Instrumentation

 

Multisegmental hook and pedicle screw systems

- compression / rotation / distraction

- correction in the coronal and sagittal planes

 

Selective versus non selective thoracic fusion in Lenke Type I Main Thoracic curve

 

Thoracicscoli

 

Selective thoracic fusion - avoid lumbar curve fixation

 

Awad et al Eur Spine J 2026

- systematic review of selective v non selective thoracic fusion Lenke Type 1 C

- shorter operative times with selective 

- improved corrections with non selective

- no difference in QOL measures

 

Schulz et al Spine 2014

- 106 patients Lenke Type 1C to 4C

- treated with selective thoracic fusion

- adequate correction if lumbar curve < 45° / bending lumbar Cobb angle < 25° 

 

Low versus high density pedicle screw

 

ScoliScoliosis Fusion Long Thoracic

 

Aoun et al Spine Deform 2024

- systematic review of 24 cases and 2000 patients

- some better radiographic outcomes with high density screw use

- no difference in QOL

- increased cost and operative time with high density screw use

 

Hybrid (screw / hook) constructs versus all screw

 

scoliscoliHybridHybrid

 

Daher et al Spine Deform 2024

- systematic review of hybrid versus all screw constructs

- 28 studies and 3400 patients

- lower complication and reoperation rate with all screw constructs

- better coronal plane correction with all screw

- better sagittal plane correction with hybrid

 

Navigation

 

AISAIS

 

Chan et al Eur Spine J 2020

- systematic review of pedicle screw fixation for AIS

- free hand versus navigation techniques

- lower breach rate with navigation techniques

- longer operative times with navigation techniques

- no difference in complication rates

 

Open posterior fusion versus MIS (minimally invasive surgery)

 

Yang et al J Orthop Surg Res 2022

- systematic review of open v MIS pedicle screws for idiopathic scoliosis

- longer operative time with MIS

- reduced blood loss / reduced pain / reduced postoperative pain with MIS

 

Technique 

 

AO surgery foundation posterior instrumented fusion Lenke Type 1

 

AO surgery foundation pedicle screw insertion technique by level 

 

POSNA posterior instrumented fusion video

 

Spinal cord monitoring

 

Highly accurate at detecting spinal cord injury

- affected by other factors

- anesthesia: need total intravenous anesthesia as muscle relaxants / inhalation anesthesia affect readings

- also affected by: hypothermia, blood loss, low blood pressure

 

Somatosensory evoked potentials (SEPs)  Transcranial motor evoked potential (TcMEP)

Electrodes placed upon limbs

- median nerve / wrist, tibial nerve / popliteal fossa

- stimulate a waveform and measure in the cortex

- measure baseline

- concern with reduction in wave amplitude > 50%

Electrodes placed on scalp

- electrical stimulation measured in distal muscles

 

Technique

- 4 Poster Bed - protect eyes, knees, elbows

- no pressure on abdomen / reduce venous bleeding

- midline incision / posterior approach

- divide thoracolumbar fascia midline

- split apophysis with knife (if present)

- subperiosteal elevation strap muscles

- expose facet joints and transverse processes

- don't go between transverse processes laterally as nerve roots here

- insert pedicle screws

- rods prebent in sagittal plane

- correct coronal malalignment and rotation as able

- decorticate lamina, add bone graft along each side

 

Levels

 

Lenke Type 1: Selective versus non selective thoracic fusion

Lenke Type 2 / Double Thoracic:) Posterior stabilization to T2 to stabilize / level shoulders

Lenke Type 3 (Double Major) / Type 4 (Triple Major) / Type 6: Long posterior instrumented fusion

Lenke Type 5 (Thoracolumbar / Lumbar): Lumbar spine fusion

 

ThoracicThoracic

 

ScoliScoliScol

 

ScoliscoliScoliscoli

 

Anterior fusion

 

Results

 

Benites et al Neurosurg Rev 2025

- systematic review of anterior v posterior instrumentation

- longer operative times for anterior instrumentation

- similar blood loss and correction

- fewer instrumentated vertebrae with anterior 

 

Anterior vertebral body tethering

 

Tethering

From: Wong et al J Spine Surg 2024

 

Concept

 

Anterior vertebral body tethering

 

Youtube Zimmer Biomet Tether animation video

 

Non fusion method / growth modulation

- limit the growth of spine on one side

- allows the curve to progressively correct 

 

Thoracoscopy used to place implants into vertebral body

Strong cords link implants and prevent growth

 

Results

 

Vatkar et al Eur Spine J 2023

- systematic review of 9 studies and 200 patients mean age 12

- overcorrection 14%

- mechanical complications 28%

- pulmonary complications atelectasis / pleural effusion 10%

- tether revision 8%

- revision to spinal fusion 8%

 

Varona et al Spine Deform 2025

- vertebral tethering in 156 patients

- best outcomes and lowest revision rate in Lenke Type 5 curves

 

Complications 

 

Overall

 

Kwan et al BMC Musculoskeletal Disord 2021

- 1057 cases of surgery for AIS single center

- 87% female, mean age 16, with 47% Lenke 1 curve types

- mean operative time 2 hours

- mean blood loss 1 liter

- 5% transfusion rate

- superficial infection 1%

- deep infection 0.2%

- neurological injury 0.5% 

- 2 superior mesenteric artery syndrome

- one massive blood loss

 

Revision 

 

Dong et al Global Spine J 2024

- 1800 patients

- revision rate 2.8%

- malposition implants / infection / spinal decompensation / proximal junctional kyphosis

- revision rate lower with posterior versus anterior approach

 

ScoliosisScoliosisScoliiosis

 

Superior mesenteric artery (SMA) syndrome

 

Scoliosis correction narrows distance between aorta and SMA

- compresses duodenum

- vomiting / abdominal pain / tenderness / distention

- more likely with low BMI and sagittal kyphosis

- diagnosis with oral contrast imaging

- attempt nonoperative with nasogastric tube

- may need duodenojejunostomy (form a junction between the jejunum and the duodenum)

 

Spinal decompensation / adding on

 

Coronal plane malalignment after scoliosis surgery

 

Scoliosis

 

Proximal junctional kyphosis

 

Ji et al J Orthop Surg Res 2024

- systematic review 

- overall incidence 19%

- one quarter with Lenke Type 5 curves

 

Zhong et al World Neurosurg 2019

- systematic review

- most common with larger thoracic kyphosis / larger lumbar kyphosis

 

Back pain

 

Lumbar adjacent disc degeneration / adjacent segment degeneration

- degenerative disc disease (DDD) below lowest instrumented vertebrae

 

scoliosisscoliosisScoliosis

 

Burgos et al Eur Spine J 2024

- systematic review

- incidence of DDD of 33% mean 14 years after scoliosis surgery

- lower incidence with lowest instrumented vertebrae at or above L3 versus below L3