Early onset idiopathic

 

Definition

 

Multiple definitions based upon age

- Cobb angle < 10° in child < age 5 or 10

- before puberty

- no congenital vertebral malformation

 

More difficult management due to high growing potential

 

Can be life threatening due to respiratory compromise due to decreased thoracic height

 

Epidemiology

 

1% of idiopathic scoliosis

 

Natural history

 

Age < 1 presentation - 90 % spontaneously regress

 

Age > 1 presentation - 80% progress

 

Progression Risk

 

Cobb angle > 30° and RVAD > 20°

 

Rib-vertebral angle difference / RVAD

- AP xray

- find apex of curve 

- difference in angle at which rib meets spine 

 

Rib Vertebral angle

CT

 

Exclude congenital scoliosis

 

MRI

 

20% incidence intraspinal pathology - syrinx / tethered cord / diastematomyelia / Arnold Chiari Malformation

 

Chiari malformation Syrinx Cord tethering
Chiari malformation Syrinx Tethered cord

 

Nonoperative management

 

Indications

 

Cobb angle > 20o and RVAD > 20o

 

Serial cast

 

Technique

 

Serial elongation derotation flexion (EDF) casting

- high compliance rate

- needs to be changed every 8 - 12 weeks

- child develop risks associated with repeated general anesthesia

 

Results

 

Alassaf et al Sage Open Med 2020

- systematic review of casting in infantile idiopathic scoliosis

- mean reduction in Cobb angle 25o

 

Fedorak et al JBJS Am 2019

- 54 children mean age 2 years treated with Mehta casting with 5 year follow up

- mean initial Cobb Angle 54o

- 73% improved by at least 20o

- 50% of children had Cobb angle < 15o at most recent follow up

- best results with lower initial Cobb angle and RVAD

 

Brace

 

Indication

 

After casting

- slow curve progression

- prevent surgery

- delay surgery for as long as possible

 

Results

 

Bellamy et al Spine Deform 2025

- systematic review of bracing for early onset scoliosis in 870 patients followed to skeletal maturity

- 66% < 5o progression

- incidence of surgery 44%

 

Operative

 

Indications

 

Curves > 60o

Rapidly progressive curves

 

Options

 

Posterior growing rods - manual / magnet 

Growth modulation - vertebral body tethering

Posterior instrumented fusion 

 

Posterior growing rods

 

Concept

 

Maintain growth while correcting scoliosis

 

Traditional growing rods

 

Growing rodsGrowing rods

Globus Medical Marvel Growing Rod System 

 

Surgical lengthening every 4 - 6 months

- minimally invasive

- issues with multiple surgeries and anesthesia / wound complications / multiple irradiation 

 

Mehta et al Spine Deform 2025

- comparison of traditional growing rods to magnetically controlled growing rods

- 549 patients

- lower complications / reoperations / implant breakage in magnetically controlled

 

Magnetically controlled growing rods 

 

MagnetMagnetMagnet

Globus Medical Magec System

 

Non invasive distraction but high rate of complications

 

Thakar et al Eur Spine J 2018

- systematic review of magnet controlled growing rods

- mean correction Cobb angle 65 to 35o

- mean complication rate 45%

- anchor pull-out 12%, implant failure 12%, rod breakage 11%

- revision rate 33%

 

Wang et al Eur Spin J 2023

- meta-analysis of single versus dual growing rod for early onset scoliosis

- better correction and lower complication with dual rod