Background

 

THR Exeter Stem Fracture   THR Poly Wear   THR Uncemented Subsidence
 
Australian Joint Registry 2025

 

Reason for revision

 

19,000 first time revision THA (excluding infection)

- mean 3 - 4 years post primary THA

- fracture 29%

- loosening 28%

- instability / dislocation 26%

- other 17%

 

Survival revision THA

 

de Steiger et al CORR 2022

- Australian Joint Registry 14,000 first time revision THA

- 18 year revision rate 26%

- dislocation / instability most common cause revision 33%

- infection 23%

- loosening 23%

- fracture 10%

 

Osteolysis

 

Periprosthetic osteolysis

- biological response to particulate matter

- stimulated by wear particles / debris

 

Types of wear particles

- polyethylene

- PMMA

- Cobalt / titanium 

 
Biological response to wear particles

- small wear particles phagocytosed by macrophages but unable to digest

- stimulate release of cytotoxic factors

- aggregates more macrophages

- release TNF, IL1, IL6, PGE2

- stimulated osteoclastic bone resorption

 

Component loosening signs

 

Poly wear

Progressive radiolucent lines (RLL) around implants

 

Poly wear

 

THR Poly WearTHR Eccentric Poly Wear

 

Lucent zones

 

Femur Gruen AP zones 1 - 7  Acetabulum: Charnley Zones

Zone 1:   Greater trochanter

Zone 4:   Tip

Zone 7:   Lesser trochanter

Zone 1:  Superior 1/3

Zone 2:  Middle 1/3

Zone 3:  Inferior 1/3

Gruen Zones Charnley Zones
Uncemented femur

 

Engh classification

 

Types based on presence of radiolucent lines (RLL)

 

Type I: Stable bony ingrowth Type II: Stable fibrous ingrowth Type III: Unstable fibrous ingrowth

A.  Spot welds at end of porous coating

B.  Absence of RLL next to porous coating

C.  Calcar atrophy secondary to stress shielding

A.  No spot welds

B.  Parallel RLL about porous coating

C.  No migration

A.  Component migration

B.  Progressive increase RLL

C.  Pedestal formation (bony hypertrophy at tip)

Stable bony ingrowth

THR Uncemented Stem Spot Weld AP   THR Uncemented Proximal Stress Shielding   

Spot welds                                                                  Calcar atrophy / stress shielding          

 

Unstable femoral implant                                          

 

THR Uncemented Stem Stable sclerotic lines   THR Uncemented Subsidence

Progressive RLL                                                          Pedestal formation

 

Cemented femur loosening

 

Possible Probable Definite

Bone-cement lucency < 50%

May be due to poor cementing 

Cement-implant lucency >2mm wide

Progressive

Implant subsidence

Cement fracture

Implant fracture

Progressive cement-implant lucency

Breakdown proximal cement

Cemented Femur Possible Loose Cemented Femur Probably Loose THR Probably Loose
Uncemented acetabular loosening

 

Moore et al CORR 2006

- 3 or more 97% stable

- 2 or less, 83% unstable

 

Bone ingrowth Loosening

Absence of radiolucent lines

Presence of a superolateral buttress

Medial bone stress-shielding

Radial trabecula

Inferomedial buttress

Radiolucent lines that appear after two years

Progression of radiolucent lines after two years

Radiolucent lines in all three zones

Radiolucent lines 2 mm or wider in any zone

Migration > 2mm

THR Uncemented Cup Superolateral Buttress 2 Loose Uncemented Cup

 

Engh classification

 

I  Osse-ointegration II Stable fibrous ingrowth III Unstable fibrous ingrowth

A  No RLL

B  One RLL zone 1 or 2

C  RLL zones 1 & 2

< 2 mm zone 3 > 2mm RLL in zone 3
THR Uncemented Cup Stable RLL Zone 1 Uncemented Cup Stable Fibrous Ingrowth Loose Uncemented Cup 2

Outcomes of revision THA

 

Component revision

 

Femoral stem revision only

 

Hanif et al J Arthroplasty 2020

- systematic review of 700 femoral only revision

- revision rate 7% at 9 years

 

Acetabular revision only

 

Poursalehian et al Arch Orthop Trauma Surg 2024

- systematic review of 3500 revision THA 

- acetabular revision with retention of well fixed femoral stem

- 10 year femoral stem revision: 2%

- lower femoral stem loosening with ceramic heads

 

Complications

 

Dislocation

 

Guo et al Int J Surg 2017

- systematic review of dislocation after 4600 revision THA

- incidence dislocation 9%

- increased risk: young age, history dislocation, > 2 previous revisions

- reduced risk: elevated rim liners

 

de Steiger et al CORR 2022

- Australian Joint Registry 14,000 first time revision THA

- 18 year revision rate 26%

- dislocation / instability most common cause revision 33%

- reduced revision for dislocation with dual mobility / heads > 32 mm

- higher revision for cemented femoral stems first 6 years

 

Hoskins et al CORR 2022

- Australian Joint registry 1295 first time revision

- dual-mobility construct versus large femoral heads

- dislocation rate 4% with no difference between groups

 

Infection

 

Gold et al Ann Transl Med 2019

- 8500 revision THA from National Database

- overall infection rate 3%

- deep infection rate 1%

 

de Steiger et al CORR 2022

- Australian Joint Registry 14,000 first time revision THA

- revision for infection 23% at 18 years

 

Extended antibiotics

 

Dasari et al J Arthroplasty 2024

- systematic review of extended antibiotics > 24 hours versus < 24 hours

- no observed benefit for revision of aseptic THA