platelets

Blood Products

Ultimate goal of blood management is to AVOID allogenic blood transfusion

Increased infection rate

- demonstrated in THR

- decreased killer T cells

Increased risk disease transmission

Increased risk transfusion reaction

Increased post-op fever and antibiotic requirements

Increased cost

To produce sufficient thrombin to rapidly convert soluble fibrinogen into insoluble mass of fibrin

Coagulation cascade must be localised & limited to site of tissue injury

1. Immediate Control of Blood Loss

Vascular Phase

- damage to blood vessel triggers reflex vasoconstriction

Platelet phase