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Eosinophilic Granuloma

Definition

 

Langerhan's Cell Histiocytosis

- non-neoplastic disorder

- characterised by infiltration by histiocytic cells (Monocyte / macrophage lineage)

 

Group of granulomatous inflammatory processes of unknown aetiology

- involve the reticuloendothelial component of the bone marrow, parenchymal organs, and skin

 

Types 

 

E - H - L

 

Thoracic Disc Disease

Epidemiology

 

0.05% incidence

- rare due to stabilising effect of rib cage

- even more rare to have symptoms

 

Reasoning

1.  Discs are narrower

2.  Foramina larger

3.  Thoracic spine

- facet joints orientated for rotation

- lumbar spine for flexion extension

- flexion is typically the motion which ruptures annulus

 

Anatomy